【摘 要】
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After cells divide,the new cells have to synthesize all the necessary cellular com-ponents in time for the next division.There is a lower bound of time required
【机 构】
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State Key Laboratory of Biocontrol,School of Life Sciences,Sun Yat-sen University,China
论文部分内容阅读
After cells divide,the new cells have to synthesize all the necessary cellular com-ponents in time for the next division.There is a lower bound of time required for cells to double their contents.For mammalian cells,this lower bound may be around 20 hours,as artificial selection for faster-dividing cells has not pushed cell lines to go below this 'barrier'in dou-bling time.The occasional exceptions are those that appear to 'prove the rule'.For example,yeast cells can divide once ev-ery 1.5 hours[1,2],and the fastest rate of cell divisions in metazoans maybe that of the embryonic cells of Drosophila,at 5 minutes per cycle[3].Thus,at least for eukaryotic cells,the rate-limiting step is not the replication of DNA.
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