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慢性心衰（ＣＨＦ）合并室性心律失常（ＶＡ）同时伴心率变异（ＨＲＶ）下降（ＳＤＮＮ＜７０ｍｓ）８４例，给予小剂量美托洛尔治疗，剂量为１２．５～５０ｍｇ／ｄ，观察治疗前后动态心电图（ＤＣＧ）及ＨＲＶ改变。治疗前ＤＣＧ发现简单型ＶＡ３１例，复杂型ＶＡ３６例，短阵室速２６例，ＨＲＶ下降程度与ＶＡ严重程度相一致。治疗后冠心、高心、扩心、风心病组有效率分别为８７．８％，７６．９％，８４．６％，６６．７％。说明适当剂量美托洛尔可作为治疗ＣＨＦ伴ＶＡ基础药物之一。
Eighty-four patients with chronic heart failure (CHF) combined with ventricular arrhythmia (VA) with concomitant heart rate variability (HRV) (SDNN <70 ms) were given low dose metoprolol at a dose of 12.5-50 mg / Changes of dynamic electrocardiogram (DCG) and HRV before and after treatment. Before treatment, DCG found simple VA31 cases, complex VA36 cases, short tachycardia in 26 cases, the degree of reduction of HRV consistent with VA severity. After treatment, the effective rate of coronary heart, high heart, heart expansion and rheumatic heart disease were 87.8%, 76.9%, 84.6% and 66.7% respectively. Describe the appropriate dose of metoprolol can be used as the treatment of CHF with VA one of the basic drugs.