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目的探讨脑梗死患者血清中超敏C反应蛋白(hs-CRP)、同型半胱氨酸(Hcy)水平在脑梗死中的变化及其影响。方法选取来本院就诊的脑梗死患者985例及对照组813例(其中非脑梗死249例,健康体检者564例),分别用免疫散射比浊法、循环酶法检测hs-CRP、Hcy的含量并观察其结果。结果 985例脑梗死患者hs-CRP含量为(12.62±41.75)mg/L,Hcy含量为(18.52±11.34)μmol/L;健康体检者hs-CRP含量为(6.20±8.79)mg/L;非脑梗死患者Hcy含量为(14.40±7.64)μmol/L。脑梗死组Hcy、hs-CRP水平明显高于对照组(P均<0.01)。结论脑梗死患者hs-CRP、Hcy增高,联合检测动态观察对脑梗死的病情及预后判断有一定参考价值。
Objective To investigate the changes of serum hs-CRP and homocysteine (Hcy) in patients with cerebral infarction after cerebral infarction. Methods 985 cases of cerebral infarction and 813 cases of control group (including 249 cases of non-cerebral infarction and 564 cases of healthy subjects) were enrolled in this study. The levels of hs-CRP, Hcy Content and observe the result. Results The hs-CRP level was (12.62 ± 41.75) mg / L and the Hcy level was (18.52 ± 11.34) μmol / L in 985 patients with cerebral infarction. The hs-CRP level in healthy subjects was (6.20 ± 8.79) mg / Hcy content in patients with cerebral infarction was (14.40 ± 7.64) μmol / L. The levels of Hcy and hs-CRP in cerebral infarction group were significantly higher than those in control group (all P <0.01). Conclusions The hs-CRP and Hcy in patients with cerebral infarction are increased. The dynamic observation of combined detection has certain reference value for the evaluation of the prognosis and prognosis of cerebral infarction.