论文部分内容阅读
目的:观察和探讨糖尿病视网膜病变与脂质代谢和脂质过氧化反应的关系。方法:对30名早期糖尿病视网膜病变患者与24名健康人空腹血清中甘油三脂(TC),总胆固醇(TG),高密度脂蛋白—胆固醇(HDL—C),低密度脂蛋白—胆固醇(LDL—C),过氧化物歧化酶SOD)和脂质过氧化物(LPO)的含量进行了检测。结果:发现患者组中TC、TG、LDL—C与LPO均明显高于对照组,而HDL—C与SOD都低于健康对照组。结论:糖尿病引起的脂质代谢紊乱和脂质过氧化反应的增强可能是促进视网病变的危险因素之一。眼科学报1998;14:100—102。
Objective: To observe and explore the relationship between diabetic retinopathy and lipid metabolism and lipid peroxidation. Methods: The fasting serum triglyceride (TC), total cholesterol (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) were measured in 30 patients with early diabetic retinopathy and 24 healthy individuals LDL-C), superoxide dismutase SOD and lipid peroxide (LPO) were detected. Results: The levels of TC, TG, LDL-C and LPO in the patients were significantly higher than those in the control group, while the levels of HDL-C and SOD were lower than those in the healthy controls. Conclusion: The disorder of lipid metabolism and the increase of lipid peroxidation caused by diabetes may be one of the risk factors to promote retinopathy. Ophthalmic Science 1998; 14: 100-102.