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目的:观察腹腔镜病灶切除术联合戈舍瑞林治疗子宫腺肌瘤的临床疗效。方法:选取30例子宫腺肌瘤患者行腹腔镜病灶切除术,术后予戈舍瑞林治疗3个月。结果:30例患者手术及戈舍瑞林治疗后痛经缓解率为100%;月经量较术前明显减少(P<0.01);月经周期和经期无明显改变(P>0.05);有8例患者药物副反应表现为低雌激素水平症状如潮热、多汗、阴道干燥、性欲下降等,全部患者肝功能无明显变化;1例患者复发。结论:腹腔镜病灶切除术联合戈舍瑞林治疗子宫腺肌瘤能有效缓解痛经、经血过多等症状,保留了患者的生育器官,是一种有效、微创、安全的治疗方法。
Objective: To observe the clinical effect of laparoscopic resection combined with goserelin in the treatment of adenomyosis. Methods: Thirty patients with adenomyosis underwent laparoscopic resection of the lesion and treated with goserelin for 3 months postoperatively. Results: The rate of dysmenorrhea was 100% after surgery and goserelin treatment in 30 patients. The amount of menstruation was significantly lower than that before operation (P <0.01), but there was no significant change in menstrual cycle and menstruation (P> 0.05) Side effects of drugs showed low estrogen levels such as hot flashes, sweating, vaginal dryness, loss of libido, all patients had no significant change in liver function; 1 patient relapsed. Conclusion: Laparoscopic resection combined with goserelin in the treatment of adenomyosis can effectively relieve symptoms such as dysmenorrhea and menorrhagia and preserve the reproductive organs of patients. It is an effective, minimally invasive and safe treatment.