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血清高敏C-反应蛋白(hs-CRP)、白细胞介素-6(IL-6)以及肿瘤坏死因子-α(TN F-α)水平为冠状动脉疾病(CAD)患者不良预后的预测因素。作者推测,炎症标记物检测可以预测动脉粥样硬化负荷和主要不良心血管事件(MACE)。前瞻性检测249例因急性胸痛入院并接受冠状动脉血管造影的患者的hs-CRP、IL-6及TNF-α,分析炎症标记物水平与冠状动脉造影CAD严重程度之间的关系。
Serum high sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6) and tumor necrosis factor-α (TN F-α) levels were predictors of poor prognosis in patients with coronary artery disease (CAD). The authors hypothesize that markers of inflammation can predict atherosclerotic burden and major adverse cardiovascular events (MACE). The prospective study of hs-CRP, IL-6 and TNF-α in 249 patients admitted to hospital for acute chest pain who underwent coronary angiography was performed to analyze the relationship between the level of inflammatory markers and CAD severity of coronary angiography.