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目的:探讨联合用药对治疗类风湿关节炎的临床疗效。方法:选取我院2003-2010年收治的80例类风湿患者,男45例,年龄45-78岁,病程6-20个月,女35例,年龄40-80岁,病程6-24个月。随机分成两组,观察组患者40例,用药MTX+LEF,对照组患者40例,用药MTX。结果:观察组患者出现的不良反应中,重度1例,中度7例,轻度15例,对照组患者出现的不良反应中,重度3例,中度10例,轻度20例,结论:联合用药治疗类风湿关节炎效果优于单一用药治疗,对于治疗类风湿关节炎应当注重联合用药,以保证治疗效果。
Objective: To investigate the clinical effect of combination therapy on rheumatoid arthritis. Methods: Eighty patients with rheumatoid arthritis admitted in our hospital from 2003 to 2010 were selected, including 45 males and 45 females aged from 45 to 78 with a duration of 6 to 20 months and 35 females aged 40 to 80 years with a duration of 6 to 24 months . Randomly divided into two groups, observation group of 40 patients, medication MTX + LEF, 40 patients in the control group, medication MTX. Results: Among the adverse reactions observed in the observation group, there were 1 severe case, 7 moderate cases and 15 mild cases. Among the adverse reactions in the control group, 3 cases were severe, 10 cases were moderate and 20 cases were mild. Conclusion: Combination therapy for rheumatoid arthritis is better than single drug treatment, for the treatment of rheumatoid arthritis should pay attention to combination therapy to ensure the treatment effect.