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自三十年代发现流行性出血热(EHF)以来,为了分离病毒,探讨实验敏感动物和组织培养方法,花了四十年时间。陕西于1955年发现EHF,1959—1980年对EHF疫区和非发病区进行了长期研究,1973—1975年做了专题调查,随后取得了血清学调查数据,首次提出汉中县为非疫区,1976年应用非疫区原代黑线姬鼠淡色亚种(Apodemus agrarius pallidior)为实验动物来分离EHF病毒,1977年从EHF病人早期血液标本中分离到4株病毒。同时,根据中国医学科学院病毒学研究所的要求以及全国病原研究协作会议纪
Since the discovery of Epidemic Haemorrhagic Fever (EHF) in the 1930s, it has taken 40 years to isolate sensitive viruses and to explore methods of culturing sensitive animals and tissues. Shaanxi found EHF in 1955, conducted a long-term study of the EHF epidemic and non-endemic areas in 1959-1980, conducted a special survey in 1973-1975, and subsequently obtained serological survey data. It was the first time that Hanzhong County was designated as a pest free area, In 1976, EHF virus was isolated from experimental non-infected area of Apodemus agrarius pallidior. Four viruses were isolated from early blood samples of EHF patients in 1977. At the same time, according to the requirements of the Institute of Virology of the Chinese Academy of Medical Sciences and the National Conference on Pathogen Research