重症肝炎治疗的探索——肝再生刺激因子的研究

• 作 者: 童善庆 李彪如
• 机 构: 上海第二医科大学,上海第二医科大学,
• 出 处: 国外医学.流行病学传染病学分册
• 发表日期: 1988年03期
• 关键词: 暴发型肝炎 人工肝辅助装置 肝再生 肝细胞 存活率 肝细胞坏死 血浆交换 肝炎 病死率 半乳糖胺

暴发型肝炎患者由于肝细胞大量坏死,肝功能严重损害,因而病死率很高。国外曾先后采用全血及血浆交换疗法、体外吸附剂灌流以及人工肝辅助装置等治疗措施,但存活率仍低于30～40%。近年来,为了降低暴发型肝炎患者的病死率,提高存活率,许多学者在努力寻找既能阻止肝细胞坏死,又能促进肝细胞再生的物质或药物,先后研究了胰

Patients with fulminant hepatitis due to massive necrosis of liver cells, severe liver damage, and thus high mortality. Foreign countries have successively adopted whole blood and plasma exchange therapy, in vitro adsorbent perfusion and artificial liver aids and other treatment measures, but the survival rate is still below 30 to 40%. In recent years, in order to reduce mortality and improve the survival rate of patients with fulminant hepatitis, many scholars are trying to find a substance or drug that can both prevent liver cell necrosis and promote liver cell regeneration.