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目的 探讨介入化疗栓塞治疗巨块型宫颈癌的临床疗效。方法 对 38例巨块型宫颈癌患者采用超选择子宫动脉灌注 5 -氟尿嘧啶 (5 - Fu) ,顺铂 (PDD) ,丝裂霉素 (MMC)加超液化碘油行子宫动脉化疗栓塞。结果 盆腔动脉造影能清楚显示肿瘤血管、范围及位置。经介入化疗栓塞配合放疗能在短时间内控制巨大肿块 ,局部控制率达 92 .10 % ,而单纯放疗局部控制率为70 .45 % ,P<0 .0 5。两者有显著差异。结论 介入化疗栓塞能够提高巨块型宫颈癌近期疗效。
Objective To investigate the clinical effect of interventional chemoembolization in the treatment of massive cervical cancer. Methods Thirty - eight patients with massive cervical cancer were treated with superselective uterine artery perfusion of 5 - Fu, PDD, MMC and ultrasonified liquefied iodized oil for uterine artery chemoembolization. Results pelvic artery angiography can clearly show the tumor blood vessels, extent and location. After interventional chemotherapy and embolization combined with radiotherapy can control huge tumor in a short time, the local control rate was 92.10%, while the local control rate of radiotherapy alone was 70.45%, P <0.05. There are significant differences between the two. Conclusion Interventional chemotherapy embolization can improve the curative effect of massive cervical cancer.