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目的观察医用几丁糖预防剖宫产术后组织粘连的临床效果。方法 108例行二次剖宫产患者,其中58例第一次剖宫产时应用几丁糖预防组织粘连(治疗组),50例第一次剖宫产时不使用任何预防粘连的药物(对照组)。观察第一次剖宫产术后腹痛情况以及第二次剖宫产术时的盆腹腔粘连情况。结果第一次剖宫产术后,治疗组腹痛发生率(6.9%)明显低于对照组(16.0%),差异有统计学意义(P<0.05)。第二次剖宫产术时,治疗组预防粘连有效率为81.0%,对照组为56.0%,比较差异有统计学意义(P<0.05)。结论医用几丁糖预防剖宫产术后组织粘连效果显著,值得在临床中推广应用。
Objective To observe the clinical effect of medical chitosan in preventing tissue adhesion after cesarean section. Methods A total of 108 patients undergoing secondary cesarean delivery were enrolled. Among them, 58 cases were given chitosan to prevent tissue adhesion in the first cesarean section (treatment group), and 50 cases did not use any drug to prevent adhesion in the first cesarean section Control group). Observe abdominal pain after the first cesarean section and pelvic adhesions during the second cesarean section. Results After the first cesarean section, the incidence of abdominal pain in the treatment group (6.9%) was significantly lower than that in the control group (16.0%). The difference was statistically significant (P <0.05). In the second cesarean section, the effective rate of prevention of adhesion was 81.0% in the treatment group and 56.0% in the control group, the difference was statistically significant (P <0.05). Conclusion The clinical effect of chitosan for prevention of tissue adhesion after cesarean section is significant and it is worth to be popularized in clinic.