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目的调查黑龙江省成年人高胆固醇血症、高低密度脂蛋白血症、低高密度脂蛋白血症和高甘油三酯血症的患病率,分析其流行特点。方法采用多阶段分层整群抽样方法,在黑龙江省10个监测点调查5 998名成年人,抽取到5 969名成年人空腹外周静脉血,进行血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)和甘油三酯(TG)检测。对样本复杂加权后,分别计算高胆固醇血症、高密度脂蛋白血症、低密度脂蛋白血症和高甘油三酯血症患病率。结果黑龙江省成年人口中高胆固醇血症、高密度脂蛋白血症、低密度脂蛋白血症和高甘油三酯血症的患病率分别为6.19%(城市7.59%、农村5.20%)、8.05%(城市10.29%、农村6.47%)、26.75%(城市27.13%、农村26.48%)和16.65%(城市18.25%、农村15.52%),不同地区患病率差异有统计学意义(P<0.01)。结论黑龙江省成年人血脂异常以低密度脂蛋白血症和高甘油三酯血症为主,城市患病率高于农村,随体质量指数(BMI)增高患病率增高明显。
Objective To investigate the prevalence of hypercholesterolemia, high and low-density lipoproteinemia, low-density lipoproteinemia and hypertriglyceridemia in adults in Heilongjiang Province, and to analyze its epidemiological characteristics. Methods A multistage stratified cluster sampling method was used to investigate 5 998 adults at 10 monitoring points in Heilongjiang Province. A total of 5 969 adult fasting peripheral blood samples were collected for serum total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG). After complex weighting of samples, the prevalences of hypercholesterolemia, HDL, LDL and hypertriglyceridemia were calculated separately. Results The prevalence rates of hypercholesterolemia, high density lipoproteinemia, low density lipoproteinemia and hypertriglyceridemia in adult population in Heilongjiang Province were 6.19% (7.59% in urban and 5.20% in rural areas), 8.05% (10.29% in urban areas and 6.47% in rural areas), 26.75% (27.13% in urban areas, 26.48% in rural areas) and 16.65% (18.25% in urban areas and 15.52% in rural areas). The prevalence in different areas was significantly different (P <0.01). Conclusion The prevalence of dyslipidemia in adults in Heilongjiang Province is mainly low-density lipoproteinemia and hypertriglyceridemia. The prevalence in urban areas is higher than that in rural areas. The prevalence increases with the increase of body mass index (BMI).