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目的分析乙型肝炎患者进行免疫球蛋白检测的临床意义与价值。方法收集2014年1月~2015年1月期间,临床确诊为乙型肝炎的患者120例作为研究对象。根据病情分组,30例急性乙型肝炎为A组,30例慢性乙型肝炎为B组,30例慢性重型乙型肝炎为C组,30例肝硬化为D组。同时将30例排除乙型肝炎的健康体检者作为对照组。对比各组免疫球蛋白指标检测水平。结果 A、B、C、D组血清中Ig E、Ig G、Ig A水平明显高于对照组(P<0.05),其中以C组的Ig E、Ig G、Ig A、Ig M水平与对照组相比,升高最为明显,其次为D组。结论结论可将免疫球蛋白水平视为一种评判乙型肝炎患者肝功能健全程度的重要指标,并在临床上加以推广应用,提高对乙型肝炎患者病情诊断及预后判断的水平。
Objective To analyze the clinical significance and value of immunoglobulin in hepatitis B patients. Methods A total of 120 patients with clinically diagnosed hepatitis B from January 2014 to January 2015 were enrolled in this study. According to the disease group, 30 cases of acute hepatitis B for the A group, 30 cases of chronic hepatitis B for the group, 30 cases of chronic severe hepatitis B for the C group, 30 cases of cirrhosis for the D group. At the same time, 30 healthy volunteers who excluded hepatitis B were taken as the control group. The levels of immunoglobulin index in each group were compared. Results The serum levels of Ig E, Ig G and Ig A in group A, B, C and D were significantly higher than those in control group (P <0.05). The levels of Ig E, Ig G, Ig A and Ig M in group C were significantly higher than those in control group Group, the most obvious increase, followed by the D group. Conclusion Conclusions Immunoglobulin levels can be considered as an important index to evaluate the degree of liver function in patients with hepatitis B, which should be popularized and applied clinically to improve the diagnosis and prognosis of patients with hepatitis B.