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回顾分析糖尿病性肾病慢性肾功能衰竭70例,发现有6例属于无明显蛋白尿而肾功能减退的糖尿病性肾病的特殊临床类型;氮质血症早期组经降糖、降压、抗凝、低蛋白膳食等综合治疗1个月,尿总蛋白、尿白蛋白、血尿素氮(BUN)及肌肝(Cr)均降低(P<0.05或0.01),BUN和Ct均与平均动脉压相关(r各为0.314和0.337,P<0.05),说明控制高血压对迅速改善早期氮质血症患者肾功能的重要性;尿毒症期死亡者中以心力衰竭为最常见的原因(10/15),感染为最常见的诱因(14/15);本病预后差,对糖尿病患者动态监测肾功能,并对已患糖尿病性肾病,尤以氮质血症期者加强综合治疗,当有助于早期诊疗,防止病情恶化,使预后有所改善。
Retrospective analysis of 70 cases of diabetic nephropathy chronic renal failure, found that there are 6 cases of no obvious proteinuria and renal dysfunction, a special type of diabetic nephropathy; azotemia early group by hypoglycemic, antihypertensive, anticoagulant, (P <0.05 or 0.01). The BUN and Ct were significantly correlated with the mean Arterial pressure (r = 0.314 and 0.337, P <0.05), indicating that the importance of controlling hypertension for the rapid improvement of renal function in patients with early azotemia; the death of uremic patients with heart failure Is the most common cause (10/15). Infection is the most common cause (14/15). The prognosis of this disease is poor. It dynamically monitors renal function in patients with diabetes mellitus, and has already been diagnosed with diabetic nephropathy, especially azotemia Period to strengthen the comprehensive treatment, when it helps to early diagnosis and treatment to prevent deterioration of the condition, so that the prognosis has improved.