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中国第一次和第二次强化免疫日(NID)活动有效地控制和消除了儿童零剂次免疫状态的持续累积,免疫人群覆盖率显著提高,脊髓灰质炎(脊灰)野病毒病例显著下降,基本控制了脊灰野病毒病例的区域性暴发或流行,表明强化免疫措施对于在短期内阻断脊灰野病毒的传播效果显著。据免疫人群出生队列分析,我国多数省份的第二次强化免疫儿童接种数明显较第一次强化免疫提高,全国1—3岁组儿童接种数平均增加了7.9%(第一轮)和4.3%(第二轮),其中主要含有第一次强化免疫0岁组漏服儿童,而且零剂次儿童总数比第一次强化免疫减少了59.3%。零剂次儿童集中分布于0岁组,其百分构成从第一次强化免疫的66.3%升至第二次强化免疫的82.9%,表明加强和提高0岁组儿童免疫水平是保障我国强化免疫效果的有效途径。此外,在第二次全国强化免疫活动实施过程中,第二轮接种人数明显减少的具有468个,占18%,应种儿童数低于登记儿童数的县占37%,并有19%的县接种人数低于常规免疫建卡数,应针对上述问题采取有效措施。
The first and second immunization days (NIDs) in China effectively controlled and eliminated the continuous accumulation of children’s zero-dose immunization status with a significant increase in coverage of immunized groups and a significant decrease in cases of poliomyelitis (polio) wild virus , Which basically controlled the regional outbreak or epidemic of poliovirus cases, indicating that the intensive immunization measures have a significant effect in blocking the transmission of the poliovirus in the short term. According to the birth cohort analysis of immunization population, the number of vaccinated children in the second intensive immunization in most provinces in China was significantly higher than that of the first immunization. Inoculation numbers of children aged 1-3 in the country increased by an average of 7.9% (first round) and 4.3% (second round). The majority of children aged 0 in the group with primary immunization had missed the children and the number of children at zero doses was 59.3% less than the first immunization. Zero-dose children were concentrated in the 0-year-old group, and their percentages rose from 66.3% of the first booster immunization to 82.9% of the second booster immunization, indicating that strengthening and raising the immunization level of children aged 0 years was An Effective Way to Guarantee the Effect of Strengthening Immunization in China. In addition, during the implementation of the second national immunization campaign, there were 468 or 18% of the second round of immunization with a marked decrease, and 37% of the counties with children under the registered number of children accounted for 37% County vaccination is lower than the number of routine immunization card, should take effective measures to address the above problems.