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目的探讨脑梗死患者治疗前后,同型半胱氨酸(HCY)尿酸(UA)和C反应蛋白(CRP)水平的变化及意义。方法应用免疫比浊法和化学法对100例脑梗死患者进行了血浆中HCY、UA、CRP水平检测并与100例正常健康人作比较。结果治疗前脑梗死患者血浆HCY、UA、CRP水平显著高于正常对照组(P<0.01),经治疗3周后与正常组比较无显著差(P>0.05)。结论检测脑梗死患者血浆HCY、UA、CRP水平对判断病情和疗效具有重要的临床意义。
Objective To investigate the changes of homocysteine (HCY) uric acid (UA) and C-reactive protein (CRP) in patients with cerebral infarction before and after treatment. Methods Plasma neutrophil HCY, UA and CRP levels were measured in 100 patients with cerebral infarction by immunoturbidimetry and chemical method and compared with 100 healthy controls. Results The plasma levels of HCY, UA and CRP in patients with cerebral infarction before treatment were significantly higher than those in normal control group (P <0.01). After 3 weeks of treatment, the levels of HCY, UA and CRP were not significantly different from those in normal group (P> 0.05). Conclusion The detection of plasma HCY, UA and CRP levels in patients with cerebral infarction has important clinical significance in judging the disease and curative effect.