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目的 :观察海藻酸钠 -聚赖氨酸 -海藻酸钠 (ＡＰＡ)微囊化牛肾上腺嗜铬细胞 (ＢＣＣ)异种移植对慢性癌痛病人的镇痛效应、作用持续时间及不良反应。方法 :用胶原酶加机械法消化分离ＢＣＣ ;用Ｓｕｎ氏微囊制作法将ＢＣＣ包裹于ＡＰＡ微囊内。用台盼蓝、单胺 (ＳＰＧ)组织荧光法
OBJECTIVE: To observe the analgesic effect, duration of action and adverse reaction of alginate-polylysine-alginate (APA) microencapsulated bovine adrenal chromaffin cells (BCC) xenografts in patients with chronic cancer pain. Methods: BCC was digested by collagenase and mechanical method. BCC was encapsulated in APA microcapsules by Sun’s microcapsule method. Trypan blue, monoamine (SPG) fluorescence method