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由于对休克的认识,从周围循环衰竭学说转变为微循环障碍学说,因而治疗也发生相应的变化,从着重应用血管收缩剂以提高血压,转为采用血管扩张剂以增加组织的血液灌注,使休克的治愈率得到较大的提高。所以血管扩张剂治疗休克的价值,虽然在具体问题上尚有分歧,但在总的原则上已经比较统一。休克的病因虽然各不相同,其病理生理变化却具有共同的特点:即以微循环障碍为主的有效血容量的锐减和组织血液灌注量的不足。
Because of the understanding of shock, from the theory of circulating circulatory failure into microcirculation theory, so the treatment also changed accordingly, focusing on the application of vasoconstrictors to increase blood pressure, the use of vasodilators to increase tissue blood perfusion, so that Shock cure rate has been greatly improved. Therefore, the value of vasodilators in the treatment of shock, although there are differences in the specific issues, but the overall principle has been more uniform. Although the causes of shock vary, the pathophysiological changes have the same characteristics: the sharp decrease of effective blood volume mainly due to microcirculation disturbance and the shortage of tissue blood perfusion.