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作者为防治人工关节后感染及治疗慢性骨髓炎提供一种新方法,将庆大霉素渗入国产聚甲基丙烯酸甲酯(简称PMMA,在骨科又称骨水泥),PMMA选用国产TJ骨水泥和0号PMMA。对其抗菌作用、抗生素的释放、物理机械性等进行了研究。并研制成功庆大-PMMA,临床试用38例,获得满意疗效,治疗骨髓炎有效率92.9％。实验证实,庆大TJ骨水泥和0号PMMA对常见的金葡菌、大肠杆菌、变形杆菌、绿脓
The authors provide a new method for the prevention and treatment of artificial joint infection and the treatment of chronic osteomyelitis, gentamicin into domestic polymethylmethacrylate (referred to as PMMA, also known as bone cement in orthopedics), PMMA use of domestic TJ bone cement and PMMA 0. Its antibacterial activity, antibiotic release, physical and mechanical properties were studied. And the successful development of large-PMMA, clinical trial of 38 cases, access to satisfactory efficacy, the treatment of osteomyelitis effective rate of 92.9%. Experiments confirmed that Qingda TJ bone cement and PMMA 0 on the common Staphylococcus aureus, Escherichia coli, Proteus, Pus