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目的:观察中西医结合治疗老年慢性心力衰竭(CHF)的临床疗效及对血浆脑钠肽(BNP)、超敏C反应蛋白(hs-CRP)水平、超声心动图的影响。方法:将118例老年心力衰竭患者随机分为治疗组58例和对照组60例,对照组在西医常规治疗基础上加美托洛尔治疗,治疗组在对照组治疗基础上辨证给予补阳还五汤治疗。比较2组患者治疗前后左心室舒张末期内径(LVEDd)、LVEF、BNP、hs-CRP水平及综合疗效。结果:总有效率治疗组为94.8%,对照组为85.0%,2组比较,差异无统计学意义(P>0.05)。2组LVEDd、LVEF、BNP、hs-CRP治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05)。结论:中西医结合能改善老年CHF患者心功能,无明显不良反应,值得临床推广使用。
Objective: To observe the clinical efficacy of traditional Chinese and western medicine in the treatment of elderly patients with chronic heart failure (CHF) and the effects on the levels of plasma brain natriuretic peptide (BNP), hs-CRP and echocardiography. Methods: A total of 118 elderly patients with heart failure were randomly divided into treatment group (58 cases) and control group (60 cases). The control group was treated with metoprolol on the basis of western medicine routine treatment. The treatment group Soup treatment. The left ventricular end-diastolic diameter (LVEDd), LVEF, BNP, hs-CRP levels and the combined effect of two groups before and after treatment were compared. Results: The total effective rate was 94.8% in the treatment group and 85.0% in the control group. There was no significant difference between the two groups (P> 0.05). The differences of LVEDd, LVEF, BNP and hs-CRP in two groups before and after treatment and after treatment between the two groups were statistically significant (P <0.05). Conclusion: Integrative Chinese and Western medicine can improve heart function in senile CHF patients without obvious adverse reactions, and is worthy of clinical promotion.