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目的分析广东省某三甲医院抗肿瘤药物和全静脉营养液的不合理用药情况,以促进合理用药。方法收集该院静脉用药调配中心2010年6月至2011年6月间临床药师审核的抗肿瘤药物和全静脉营养液的医嘱,对其中不合理用药问题进行整理、归纳和总结,并提出合理化建议。结果审核的34 029组医嘱中,存在不合理用药的医嘱有187组。不合理用药主要表现在溶媒选择错误、用药剂量不当、用药顺序的影响、药物间相互作用和成分比例问题等方面。结论临床药师在静脉用药调配中心详细审核医嘱,可以减少和避免不合理用药的发生,促进临床安全、合理用药。
Objective To analyze the irrational use of anticancer drugs and intravenous nutrient solution in a top three hospital in Guangdong Province to promote rational drug use. Methods The prescriptions of antineoplastic drugs and parenteral nutrition approved by clinical pharmacists from June 2010 to June 2011 were collected and summarized, and the suggestions of rationalization were put forward . Out of 34,029 sets of orders examined, there were 187 sets of orders for which there was an irrational use of medication. Irrational use of drugs mainly in the wrong choice of solvent, the dosage is not appropriate, the impact of the order of treatment, drug interactions and composition ratio issues. Conclusion Clinical pharmacists in the intravenous drug deployment center detailed examination of medical advice, can reduce and avoid the occurrence of irrational drug use, promote clinical safety, rational use of medicine.