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目的:探析中晚期食道癌患者行IGRT放疗同步化疗治疗的疗效。方法:选取本院2011年9月至2013年19月收治的中晚期食道癌患者60例,根据治疗方法的不同分成对照组和观察组,各25例,其中对照组行IGRT放疗,观察组行IGRT放疗同步化疗。观察两组的疗效和不良反应。结果:观察组、对照组的总有效率分别为84%、68%,差异显著,具有统计学意义(P<0.05),两组不良反应均表现为放射性食道炎、恶心、呕吐、骨髓抑制等,各并发症发生率具有统计学意义。结论:IGRT放疗同步化疗治疗中晚期食道癌的疗效优于单纯IGRT放疗,患者可耐受不良反应。
Objective: To investigate the curative effect of synchronous chemotherapy with IGRT in patients with advanced esophageal cancer. Methods: Sixty patients with advanced esophageal cancer who were admitted to our hospital from September 2011 to September 2013 were divided into control group and observation group according to the different treatment methods, 25 cases in each group. The control group received IGRT radiotherapy and the observation group IGRT Radiotherapy Synchronous Chemotherapy. The efficacy and adverse reactions of the two groups were observed. Results: The total effective rates of the observation group and the control group were 84% and 68%, respectively, with significant difference (P <0.05). The adverse reactions in both groups were as follows: radiation esophagitis, nausea, vomiting and bone marrow suppression The incidence of complications was statistically significant. Conclusions: The efficacy of IGRT combined with radiotherapy in the treatment of advanced esophageal cancer is better than that of IGRT alone. The patients can tolerate adverse reactions.