论文部分内容阅读
目的探讨小儿支原体肺炎早期用红霉素、阿奇霉素治疗的临床疗效。方法对就诊时未明确病原体的46例肺炎患儿先用红霉素类药物治疗,给予阿奇霉素5～10mg/(kg.d)或红霉素25mg/(kg.d)静脉用药。经检测肺炎支原体抗体(MP-IgM)阳性的32例,继续用阿奇霉素治疗(疗程满7～10d后改口服,服3d,停4d)3～4周;并设确诊的肺炎支原体肺炎30例为对照组。结果支原体肺炎早期用红霉素、阿奇霉素治疗,比确诊后再换用红霉素、阿奇霉素治疗在发热、咳嗽、肺部体征改善、消失方面均有显著效果,两组治愈率经统计学处理后进行比较,均有显著效果(P<0.05);而普通肺炎患儿也未出现病情恶化,同期治愈。结论支原体肺炎早期用红霉素、阿奇霉素治疗的疗效满意,可缩短病程,减少并发症的发生,有较高的临床实用价值。
Objective To investigate the clinical efficacy of erythromycin and azithromycin in children with mycoplasmal pneumonia. Methods 46 cases of children with pneumonia who did not know the pathogen at the time of treatment were treated with erythromycin and given intravenous injection of azithromycin 5 ~ 10 mg / (kg · d) or erythromycin 25 mg / (kg · d). Thirty-two cases of positive MP-IgM antibodies were treated with azithromycin (oral administration for 7 days to 10 days, and for 3 days for 4 days) for 3 to 4 weeks. Thirty patients with confirmed mycoplasma pneumoniae pneumonia Control group. Results Mycoplasma pneumonia early with erythromycin, azithromycin treatment, than after the diagnosis and then replaced with erythromycin, azithromycin treatment in fever, cough, lung signs were improved, disappeared have a significant effect, the cure rate of both groups after statistical analysis Were compared (P <0.05), while children with normal pneumonia did not appear to be exacerbated and cured at the same period. Conclusion Mycoplasma pneumonia early with erythromycin, azithromycin treatment of satisfactory results, can shorten the course of the disease, reduce the incidence of complications, have a higher clinical value.