胰腺神经内分泌肿瘤治疗指南(2014)

• 作 者: 王春友 李非 赵玉沛 苗毅 杨尹默
• 机 构: 中华医学会外科学分会胰腺外科学组,
• 出 处: 中华普通外科学文献(电子版)
• 发表日期: 2015年03期
• 关键词: 胰腺神经内分泌肿瘤 无功能性 肝转移灶 区域淋巴结转移 胰腺切除术 胰岛素瘤 治疗指南

胰腺神经内分泌肿瘤(pancreatic neuroendocrine neoplasms,p NENs)原称为胰岛细胞瘤,约占原发性胰腺肿瘤的3%。依据激素的分泌状态和患者的表现,分为功能性和无功能性神经内分泌肿瘤。无功能性p NENs占75%~85%;功能性p NENs常见的有胰岛素瘤和胃泌素瘤,胰岛素瘤一般位于胰腺,而胃泌素瘤多见于十二指肠或胰腺。其余的功能性p NENs均少见,统称为罕见功能性胰腺神经内分泌肿瘤(rare functional pancreatic neuroen-

Pancreatic neuroendocrine neoplasms (pNENs) formerly known as islet cell tumor, accounting for about 3% of primary pancreatic tumors. According to the secretion of hormones and the performance of patients, divided into functional and non-functional neuroendocrine tumors. Non-functional p NENs accounted for 75% to 85%; functional p NENs common insulinoma and gastrinoma, insulinomas are generally located in the pancreas, and gastrinoma more common in the duodenum or pancreas. The remaining functional p NENs are rare, collectively referred to as rare functional pancreatic neuroen-