论文部分内容阅读
目的探讨甲状腺机能亢进症(甲亢)患者血清尿酸水平的变化特点。方法检测60例甲亢患者(A组)、50例亚临床甲亢患者(B组)和110例健康人(C组)血清尿酸水平。结果与C组比较,A组、B组血清尿酸水平升高(P<0.01)。A组血清尿酸水平与血清游离三碘甲腺原氨酸(FT3)、血清游离甲状腺素(FT4)呈正相关,与促甲状腺激素(TSH)呈负相关。B组、C组尿酸水平与FT3、FT4、TSH无相关性。结论甲亢患者尿酸水平升高是心血管疾病的又一高危因素。伴有高尿酸血症的甲亢患者,在积极治疗甲亢的同时,应该通过多种途径对高尿酸水平进行干预。
Objective To investigate the changes of serum uric acid in patients with hyperthyroidism (hyperthyroidism). Methods Serum uric acid levels were measured in 60 patients with hyperthyroidism (group A), 50 patients with subclinical hyperthyroidism (group B) and 110 healthy people (group C). Results Compared with group C, serum uric acid levels in group A and group B were significantly increased (P <0.01). Serum uric acid levels in group A were positively correlated with serum free triiodothyronine (FT3) and serum free thyroxine (FT4), but negatively correlated with thyrotropin (TSH). The levels of uric acid in group B and group C had no correlation with FT3, FT4 and TSH. Conclusion Hyperthyroidism patients with elevated uric acid is another risk factor for cardiovascular disease. Hyperthyroidism associated with hyperuricemia in patients with active treatment of hyperthyroidism at the same time, should be a variety of ways to interfere with high uric acid levels.