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神经胶质细胞(NG)的总体积占脑的一半,数量远远超过神经元。NG膜电位大于神经元的膜电位,且完全决定于[K~+]_0。NG 不产生动作电位。神经元与 NG 之间为细胞外间隙。神经元活动时(不论是兴奋性或抑制性神经元)有 K~+释放至细胞外间隙,引起 NG 去极化。NG 去极化值的大小反映神经元活动的数量及频率。NG 可以限制 K~+的扩散,故 NG 虽不影响神经的传导,却可影响其后电位。尚有一些令人感兴趣的问题,有待进一步澄清或深入。例如:[K~+]_0的改变是否引起 NG 的代谢反应、NG 对递质的浓度有无影响及能否调节、以及 NG 与癫痫发作有何关系等等。
The total volume of glial cells (NG) accounts for more than half of the brain, far more than the number of neurons. The membrane potential of NG is larger than the membrane potential of neurons and is completely determined by [K ~ +] _0. NG does not produce action potential. Neurons and NG for the extracellular space. Neuronal activity (whether excitatory or inhibitory neurons) K ~ + release to the extracellular space, causing NG depolarization. The magnitude of NG depolarization reflects the number and frequency of neuronal activity. NG can limit the proliferation of K ~ +, so although NG does not affect nerve conduction, but it can affect the potential after. There are still some interesting issues to be further clarified or deepened. For example: [K ~ +] _ 0 whether the change caused by metabolic reactions of NG, NG on the concentration of the transmitter has no effect and can be adjusted, and NG and the relationship between seizures and so on.