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目的:探讨前列地尔联合保肾汤治疗糖尿病肾病的临床疗效。方法:将53例糖尿病肾病患者随机分为两组,实验组给予前列地尔联合保肾汤治疗,对照组给予单纯前列地尔治疗。结果:实验组、对照组总有效率分别为92.59%、65.38%,实验组总有效率明显高于对照组,两组差异存在统计学意义(P<0.05);两组患者治疗前后UREA、CREA、UAE变化明显,存在统计学意义(P<0.01);实验组治疗后UREA、CREA、UAE变化更明显,两组差异存在统计学意义(P<0.01)。结论:前列地尔联合保肾汤治疗糖尿病肾病,可取得满意的治疗效果,疗效高,值得推广。
Objective: To investigate the clinical efficacy of alprostadil combined with Baoshen Tang in the treatment of diabetic nephropathy. Methods: Fifty-three patients with diabetic nephropathy were randomly divided into two groups. The experimental group was treated with alprostadil and Baoshen Tang, while the control group was treated with alprostadil alone. Results: The total effective rates of experimental group and control group were 92.59% and 65.38%, respectively. The total effective rate in experimental group was significantly higher than that in control group (P <0.05). The levels of UREA, CREA (P <0.01). The changes of UREA, CREA and UAE were more obvious in the experimental group after treatment, and the differences between the two groups were statistically significant (P <0.01). Conclusion: Alprostadil combined with Kidney-Nourishing Decoction in treating diabetic nephropathy can achieve satisfactory curative effect with high curative effect and worthy of popularization.