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１９８９和１９９４年两个年度中，对出生后接受过乙肝疫苗免疫接种的１～２岁幼儿复查结果显示，抗乙肝表面抗体（抗ＨＢｓ）阳性率分别为８４％和８３％，乙肝发生率不足１％，提示新生儿接种乙肝疫苗具有良好效果。１９９４年与１９８９年两个年度比较，初诊为非乙肝患儿乙型肝炎病毒感染血清标志（ＨＢＶＭ）检测比较，７月～３岁组乙肝发生率仍在８．５％不变，抗ＨＢｓ阳性率则从３２．１％上升达５８％。～７岁组乙肝总发生率从３４％降至２５％，抗ＨＢｓ阳性率从１６．４％升至２３．１％；～１４岁组乙肝发生率从３３％升至３８％，抗ＨＢｓ阳性率则从１７．６％降至１２．５％。数据表明，小儿乙型肝炎病毒感染仍较严重，５年前后均有近半数３岁以上小儿为易感儿，需要接种乙肝疫苗预防
In the two years 1989 and 1994, the results of 1 to 2-year-old children receiving hepatitis B vaccine after birth showed that the positive rates of anti-HBs were 84% and 83% respectively, and the incidence of hepatitis B was not enough 1%, suggesting that newborns vaccinated with hepatitis B vaccine has a good effect. Compared with the two years of 1994 and 1989, the newly diagnosed hepatitis B virus (HBVM) in newly diagnosed children with hepatitis B showed that the incidence of hepatitis B remained unchanged at 8.5% from July to 3 years old, and the positive rate of anti-HBs The rate rose from 32.1% to 58%. The overall incidence of hepatitis B dropped from 34% to 25% at ~ 7 years of age, the positive rate of anti-HBs rose from 16.4% to 23.1%, and the incidence of hepatitis B increased from 33% to 38% at ~ 14 years of age with anti-HBs positive The rate dropped from 17.6% to 12.5%. Data show that children with hepatitis B virus infection is still more serious, 5 years ago, nearly half of children over the age of 3 are susceptible children, need to be vaccinated against hepatitis B vaccine