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目的:评价环胞霉素A和噻替哌滴眼剂降低翼状胬肉术后复发率的效果.方法:50例(50只眼)翼状胬肉患者随机分为两组行翼状胬肉单纯切除术,一组术后局部滴用1％环胞霉素A滴眼剂,另一组术后局部滴用0.05％噻替哌滴眼剂.结果:平均随访10个月,环胞霉素A组有一例复发(复发率5％),噻替哌组有3例复发(复发率10％),均比单纯翼状胬肉切除术术后复发率(30％~88％)明显降低.结论:环胞霉素A和噻替哌可以抑制翼状胬肉切除术后胬肉组织增生,降低复发率.眼科学报1999;15:91?92.“,”Purpose: To evaluate the efficiency of Cyclosporine A and Thiotepa to decrease the postoperative recurrence rate of pterygium.Methods :50 patients (50 eyes) with pterygium were treated with bare sclera resection and divided into two groups. One group used 1% cyclosporine A eye drops, the other group used 0.05% thiotepa eye drops.Results: The average follow - up time is 10 months. The recurrence rate of cyclosporine group and thiotepa group is 5 % and 10 % .Conclusion:Cyclosporine A and Thiotepa can inhibit the hyperplasia of pterygium, and decrease the postoperative recurrence rate. Eye Science 1999; 15; 91 - 92.