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目的分析POEMS综合征患者胸腔积液的细胞学及生化学特点。方法回顾性复习和整理北京协和医院进行过胸腔穿刺检查的POEMS综合征患者的一般资料、胸腔积液细胞学检查及生化学检查资料。结果进行过胸腔穿刺检查的确诊POEMS综合征24例。其中男性11例,女性13例。发病时平均年龄为48.63岁,平均病程27.45月。查体阳性(叩浊)率66.67%(16/24)。外观以黄色混浊或微混为主(54.17%,13/24),其次是黄色透明(25.00%,6/24)。胸腔积液白细胞数211.79×106/L,单核为主,占79%。参照Light标准,渗出液占84.21%。结论本文总结的POEMS综合征胸腔积液以渗出液为主,占84.21%(Light标准)。细胞学方面,白细胞数较少,以单核为主。建议临床医生拟诊POEMS综合征时注意核实是否存在胸腔积液及其性质是否典型。
Objective To analyze the cytological and biochemical characteristics of pleural effusion in patients with POEMS syndrome. Methods The retrospective review and collation of Peking Union Medical College Hospital had pleural puncture POEMS syndrome patients with general information, pleural effusion cytology and biochemical examination data. Results Thoracentesis was confirmed in 24 cases of POEMS syndrome. Including 11 males and 13 females. The average age of onset was 48.63 years, the average duration of 27.45 months. Physical examination positive (knock turbidity) rate of 66.67% (16/24). The appearance is cloudy or slightly mixed with yellow (54.17%, 13/24), followed by yellow and transparent (25.00%, 6/24). Pleural effusion white blood cell count 211.79 × 106 / L, mononuclear, accounting for 79%. According to the Light standard, exudate accounted for 84.21%. Conclusions This study summarizes POEMS syndrome pleural effusion to exudate, accounting for 84.21% (Light standards). Cytology, fewer white blood cells to mononuclear-based. It is recommended that clinicians try to confirm the existence of pleural effusion and the nature of POEMS syndrome is typical.