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目的:了解我院早产儿宫外生长发育迟缓(EUGR)及追赶生长的情况,分析EUGR的危险因素。方法:通过2010年12月至2012年7月间我院早产儿的出生史及诊治情况,分析宫外发育迟缓的危险因素;通过随访获得其出院时、纠正胎龄3个月、6个月时的体格发育及行为智力评定指数,分析追赶生长的情况。结果:符合入选标准的114例早产儿中,按体质量、身长、头围评价出院时EUGR发生率分别为42.56%、18.35%、28.22%,纠正胎龄3个月时分别为31.6%、22.8%、35.1%,6个月时为21.1%、26.3%、31.6%。在神经行为方面,EUGR早产儿和非EUGR均有显著差异。低出生体质量是EUGR发生的独立危险因素。结论:出院后EUGR早产儿存在生长追赶的趋势,但在生长指标及神经发育方面仍然落后。早期个体化的营养支持对于预防EUGR至关重要。
OBJECTIVE: To understand the ectopic growth retardation (EUGR) and catch-up growth in preterm infants in our hospital and to analyze the risk factors of EUGR. Methods: According to the birth history and diagnosis and treatment of premature infants in our hospital from December 2010 to July 2012, the risk factors of extrauterine stunting were analyzed. At the time of discharge from follow-up, the gestational age was corrected for 3 months and 6 months When physical development and behavioral intelligence assessment index, to analyze the situation to catch up with growth. Results: Among the 114 preterm infants eligible for inclusion, the EUGR rates were 42.56%, 18.35% and 28.22% respectively at the time of discharge, according to body mass, length and head circumference. The correct rates of EUGR were 31.6% and 22.8 %, 35.1%, 21.1%, 26.3%, 31.6% at 6 months. In terms of neurological behavior, there were significant differences between EUGR pre-term and non-EUGR. Low birth weight is an independent risk factor for EUGR. CONCLUSIONS: There is a trend of catch-up growth in EUGR preterm infants after discharge but still lagging behind in growth indicators and neurodevelopment. Early individualized nutritional support is crucial for the prevention of EUGR.