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目的:探讨肺表面活性物质(PS)预防早产儿呼吸窘迫综合征(NRDS)的意义。方法:选择2006年10月～2007年10月140例早产儿作为研究对象,分为治疗组和对照组,比较两组早产儿胎龄、体重、出生窒息、性别、并发症、辅助通气例数和天数及两种肺表面活性物质的疗效。结果:应用肺表面活性物质的早产儿RDS发生率、死亡率、并发症、辅助通气例数和天数明显减少,有统计学意义(P<0.05);两种肺表面活性物质的疗效比较无统计学意义(P>0.05)。结论:早期预防性应用肺表面活性物质可提高早产儿的存活率,且减少并发症、后遗症的发生率,提高了早产儿的生存质量。
Objective: To investigate the significance of pulmonary surfactant (PS) for preventing respiratory distress syndrome (NRDS) in preterm infants. Methods: A total of 140 preterm infants from October 2006 to October 2007 were selected as study subjects and divided into treatment group and control group. The gestational age, weight, birth asphyxia, gender, complications, number of assisted ventilation And the number of days and the efficacy of two pulmonary surfactant. Results: The incidence of RDS, mortality, complications, number of assisted ventilation and the number of days in preterm infants with pulmonary surfactant were significantly decreased (P <0.05). There was no statistical difference in the efficacy of the two pulmonary surfactant Significance (P> 0.05). CONCLUSIONS: Early prophylactic use of pulmonary surfactant improves survival in preterm infants and reduces the incidence of complications and sequelae and improves the quality of life in preterm infants.