论文部分内容阅读
目的探讨宫颈毛玻璃样细胞癌的临床及病理特征,以积累经验,指导临床工作。方法运用光镜及免疫组化方法观察1例宫颈毛玻璃样细胞癌的临床及病理特征,并复习相关文献。结果光镜下肿瘤呈巢状分布,肿瘤细胞边界清楚,细胞浆丰富呈毛玻璃样透明,细胞核大,染色质较粗,异型性明显,可见到病理性核分裂像。核膜较厚,核仁明显。间质有较多嗜酸性粒细胞浸润。免疫组化:CK(+)、CEA(-)、Ki6740%(+)。PAS细胞膜(+)。患者术后23个月死亡。结论宫颈毛玻璃样细胞癌是临床极其少见的肿瘤,预后差,临床应注意鉴别。
Objective To investigate the clinical and pathological features of cervical frost-like cell carcinoma in order to accumulate experience and guide clinical work. Methods The clinical and pathological features of 1 case of glaucoma carcinoma were observed by light microscope and immunohistochemistry. The related literatures were reviewed. Results The tumors showed a nested distribution under light microscope. The tumor cells had a clear boundary. The cytoplasm was rich in vitreous hyalineity, with large nuclei, thick chromatin and obvious atypia. Pathological mitotic figures were observed. Nuclear membrane thicker, obvious nucleoli. Interstitial eosinophils more infiltration. Immunohistochemistry: CK (+), CEA (-), Ki6740% (+). PAS cell membrane (+). The patient died 23 months after surgery. Conclusions Cervical glioma-like cell carcinoma is an extremely rare tumor in clinical practice, with poor prognosis and clinical precaution.