奥曲肽治疗肝硬化上消化道出血临床疗效观察

来源 :中外医学研究 | 被引量 : 0次 | 上传用户:lvyuxuan3652008
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目的:观察和分析奥曲肽治疗肝硬化上消化道出血的临床效果。方法:选取2013年8月-2014年1月笔者所在医院收治的肝硬化上消化道出血患者56例,随机分为对照组和观察组,两组均给予恩替卡韦进行肝硬化的基础治疗,同时对照组采用垂体后叶素治疗,观察组采用奥曲肽进行治疗。连续治疗8周,观察两组患者的临床治疗效果。结果:观察组总有效率为92.86%,对照组总有效率为71.43%,观察组的治疗效果优于对照组,差异有统计学意义(P<0.05)。观察组临床症状、体征恢复时间优于对照组(P<0.05)。结论:在基础治疗基础上加用奥曲肽治疗肝硬化上消化道出血疗效好。 Objective: To observe and analyze the clinical effect of octreotide on cirrhosis and upper gastrointestinal bleeding. Methods: From August 2013 to January 2014, 56 patients with cirrhosis and upper gastrointestinal bleeding admitted to our hospital were randomly divided into control group and observation group. Both groups were given basic therapy of entecavir for cirrhosis. At the same time, Group treated with pituitrin, the observation group treated with octreotide. Continuous treatment for 8 weeks, the clinical efficacy of two groups were observed. Results: The total effective rate was 92.86% in the observation group and 71.43% in the control group. The therapeutic effect of the observation group was better than that of the control group (P <0.05). The observation group had better clinical symptoms and signs recovery time than the control group (P <0.05). Conclusion: Based on the basic treatment plus octreotide treatment of cirrhosis of upper gastrointestinal bleeding is effective.
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