Improvement of Thioester Method by Using Pac Ester for Synthesis of Cyclopentapeptides

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Thioester method was improved by using Pac (phenacyl group) ester as protecting group of 3-mercaptopropionic acid. Two cyclopentapeptides c(Ala-Tyr-Leu-Ala-Gly) and c(Pro-Tyr-Leu- Ala-Gly) were synthesized successfully by this method.
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