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目的观察大鼠在７０００ｍ高度（每天１．５ｈ），不同时间机体主要脏器中铁的变化。方法Ｗｉｓｔａｒ大鼠６０只，随机分成缺氧１０天组、缺氧２０天组和对照组。将两缺氧组大鼠放入人体低压舱内，上升到７０００ｍ高度，停留１．５ｈ，每日１次。用ＷＦＸ－Ⅱ型原子吸收分光光度计测定大鼠心、脑、肝、脾、肺及血浆中铁的含量。结果低压缺氧使大鼠机体血浆、脑、肝及脾中铁含量明显降低，而心和肺中铁含量明显增加。结论低压缺氧暴露可使大鼠机体主要脏器中铁含量发生变化，提示对短期进入高原低压缺氧环境的作业的人群，在营养卫生保障工作中应增加铁的摄入量。
Objective To observe the changes of iron in major organs at 7000m (1.5h daily) and at different time points. Methods Sixty Wistar rats were randomly divided into 10 days hypoxia group, 20 days hypoxia group and control group. The two hypoxia rats into the body low pressure cabin, rose to 7000m height, stay 1.5h, 1 times daily. The contents of iron in heart, brain, liver, spleen, lung and plasma were determined by WFX-Ⅱ atomic absorption spectrophotometer. Results Hypobaric hypoxia significantly reduced the content of iron in the plasma, brain, liver and spleen of rats, while the content of iron in heart and lung increased significantly. Conclusions Hypoxia and Hypoxia exposure can change the content of iron in the main organs of rats, suggesting that iron intake should be increased in the work of nutrition and health protection for short-term entry into the low-pressure anoxic environment.