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用双氢青蒿素在食蟹猴疟原虫－大劣按蚊猴疟模型中的试验结果显示：给感染猴一次性口服４０ｍｇ／ｋｇ双氢青蒿素之后，５ｈ内疟原虫总数变化不明显，配子体数量仍继续增加，各期原虫形态观察无改变。但用药后１．５ｈ吸血感染蚊胃内平均卵囊感染数开始明显下降，５ｈ后蚊胃未发现卵囊。结果提示：双氢青蒿素不仅具有速效杀灭疟原虫无性体、复燃率低、剂量少的特点，而且用药后能快速降低食蟹猴疟原虫传疟按蚊蚊胃卵囊感染数，用药５ｈ后可阻断吸血蚊疟原虫孢子增殖期的发育。
The test results of dihydroartemisinin malaria cynomolgus-anopheles malariae malaria model showed that after a single oral administration of 40 mg / kg dihydroartemisinin to infected monkeys, the total number of malaria parasite was insignificant within 5h , The number of gametophytes continued to increase, and the morphological observation of protozoa did not change in all stages. However, the average number of oocysts in the mosquito infected by vomiting at 1.5h after injection dropped significantly, and no oocysts were found in the mosquito stomach after 5h. The results suggest that dihydroartemisinin not only has the advantage of quick killing Malagasy parasite asexuality, low revival rate and low dosage, but also can rapidly reduce the number of mosquito stomach oocysts in malaria parasite, 5h after treatment can block the development of spores of M. malariae.