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目的探讨分析早期机械通气对重型颅脑损伤并神经源性肺水肿(NPE)的疗效。方法 62例重型颅脑损伤并神经源性肺水肿患者,按照入院顺序分为甲组和乙组,每组31例。甲组患者通过早期机械通气进行治疗,乙组患者通过常规机械通气进行治疗。对比两组患者的格拉斯哥昏迷评分(GCS)、撤机时间以及格拉斯哥预后评分(GOS)。结果甲组患者治疗后的GCS评分为(12.21±2.47)分,高于乙组的(8.45±2.11)分,差异具有统计学意义(P<0.05)。甲组患者的撤机时间为(7.17±2.34)d,短于乙组的(12.36±3.41)d,差异具有统计学意义(P<0.05)。甲组患者的生存质量情况优于乙组患者,差异具有统计学意义(P<0.05)。结论对于重型颅脑损伤并神经源性肺水肿患者来说,早期给予机械通气可明显改善患者的昏迷情况,缩短患者的机械通气时间,并有效改善了患者的生存质量,值得推广。
Objective To investigate the effect of early mechanical ventilation on severe craniocerebral injury and neurogenic pulmonary edema (NPE). Methods Sixty-two patients with severe craniocerebral injury and neurogenic pulmonary edema were divided into group A and group B according to admission sequence, with 31 cases in each group. Patients in group A were treated by early mechanical ventilation and patients in group B were treated by conventional mechanical ventilation. Glasgow Coma Scale (GCS), weaning time, and Glasgow Outcome Scale (GOS) were compared between the two groups. Results The score of GCS after treatment in group A was (12.21 ± 2.47) points higher than that in group B (8.45 ± 2.11), the difference was statistically significant (P <0.05). The weaning time of group A was (7.17 ± 2.34) d, shorter than that of group B (12.36 ± 3.41) d, the difference was statistically significant (P <0.05). The quality of life of patients in group A was better than that of patients in group B, the difference was statistically significant (P <0.05). Conclusion For patients with severe craniocerebral injury and neurogenic pulmonary edema, the early mechanical ventilation can significantly improve the patients coma, shorten the duration of mechanical ventilation and effectively improve the quality of life of patients, which is worth promoting.