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杀精子药都是在生物学上能明显阻断生育力的一种药物。这类药物在发展中国家和发达国家中的应用正在不断地增加。遗憾的是这类药物的选择品种目前不多,因此发展新杀精子药是很重要的一个课题。壬苯醇醚(NP-9)是目前最广泛应用的一种杀精子药,它是一种非离子型表面活性剂。这类药可立即导致精子不能游动,从而无法使卵受精。不过目前人们对这种药的毒性仍然存在争议。至今明显的一种有害的实验发现是阴道应用壬苯醇醚杀精药后可降低血浆胆固醇水平。洗必泰是五十年代初期发现的一种消毒剂,它具有破坏细胞的渗透性屏障和阻断细胞色素系中电子传递的双重杀菌能力。目前在医药上已广泛应
Spermicide drugs are biologically significant drugs that block fertility. The use of such drugs in developing and developed countries is steadily increasing. Unfortunately, the selection of such drugs is currently small, so the development of new spermicide drugs is a very important issue. Nonoxynol (NP-9) is currently the most widely used spermicide, a non-ionic surfactant. Such drugs can immediately lead to sperm can not swim, which can not fertilize the eggs. However, the toxicity of this medicine remains controversial. So far a clear experimental result is harmful to the vaginal application of nonoxynol spermicide can reduce plasma cholesterol levels. Chlorhexidine was a disinfectant found in the early 1950s that had the dual bactericidal effect of disrupting the cell’s permeability barrier and blocking the electron transport in the cytochromes. It is widely used in medicine