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目的观察和探讨血清胆红素与冠状动脉粥样硬化性心脏病患者及其病变严重程度的关系。方法测定非冠心病患者61例(对照组),冠心病患者151例(冠心病组)的血清胆红素水平,以冠状动脉造影结果作为分组依据,并分析血清总胆红素水平与冠状动脉病变Gensini评分的关系。结果冠心病组血清间接胆红素水平明显低于对照组(P<0.05);冠心病组与对照组之间总胆红素、直接胆红素水平差异无统计学意义(P>0.05);但是血清间接胆红素水平与Gensini评分间无相关关系(P>0.05)。结论冠心病患者血清间接胆红素水平明显降低,但是与冠状动脉病变程度无明显相关关系,需要进一步分析。
Objective To observe and explore the relationship between serum bilirubin and coronary heart disease in patients with coronary heart disease severity. Methods Serum bilirubin levels were measured in 61 patients with coronary heart disease (control group) and 151 patients with coronary heart disease (CHD). The coronary angiography results were used as the basis for grouping. The levels of serum total bilirubin and coronary artery Relationship between lesion Gensini score. Results The level of serum indirect bilirubin in CHD group was significantly lower than that in control group (P <0.05). There was no significant difference in total bilirubin and direct bilirubin between CHD group and control group (P> 0.05). However, there was no correlation between serum bilirubin and Gensini scores (P> 0.05). Conclusion Serum levels of indirect bilirubin in patients with coronary heart disease were significantly lower than those in patients with coronary artery disease, but there was no significant correlation between the levels of indirect bilirubin and coronary artery disease.