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目的 观察静脉滴注胺碘酮在急性冠状动脉综合征(ACS)伴快速房颤患者的临床疗效。方法 20例ACS患者伴新近发生快速房颤,静脉应用胺碘酮,先静脉注射负荷量后,继以静脉滴注维持观察房颤转复及心室率控制及不良反应。结果 20例患者心率用药后较用药前明显下降(P<0.01)。其中14例患者(70%)在24 h内转为窦性心律,3例用药后出现长R-R间期,3例出现窦性心动过缓,经停药或减药后恢复。结论静脉应用胺碘酮治疗ACS伴快速房颤是有效及安全的。
Objective To observe the clinical effect of intravenous drip amiodarone in patients with acute coronary syndrome (ACS) and rapid atrial fibrillation. Methods Atrial fibrillation (AF), ventricular rate control and adverse reactions were observed in 20 patients with ACS accompanied by atrial fibrillation. Intravenous Amiodarone (IV) was given intravenously before loading. Results The heart rate of 20 patients was significantly lower than that before treatment (P <0.01). Among them, 14 patients (70%) were converted to sinus rhythm within 24 h. Three patients showed long R-R interval, three patients had sinus bradycardia and recovered after stopping or reducing medication. Conclusion Intravenous amiodarone is effective and safe in the treatment of ACS with rapid atrial fibrillation.