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目的了解我国肝脏肿瘤的发生特点及其临床病理特征。方法用常规病理方法分析了手术切除的3160例肝脏肿瘤的构成及临床病理特点,共涉及三个胚层来源的25类肿瘤。结果肝脏瘤样病变4种,112例,占3.5%,肝脏良性肿瘤10种,499例,占15.8%,肝脏恶性肿瘤11种,2549例,占80.7%。三组中最为常见的分别是炎性假瘤(占该组的73.2%),肝海绵状血管瘤(占该组的74.3%)和肝细胞癌(占该组的96.8%)。三组患者在年龄与性别比上有所不同。肝细胞癌的血清HBsAg阳性率和肝硬化伴发率分别为74.4%和72.0%,<3cm小肝癌的肝硬化合并率高达83.2%。结论结果表明,HBV感染和肝硬化与肝细胞癌的发生有密切关系。
Objective To understand the occurrence characteristics and clinicopathological features of liver tumors in China. METHODS: The pathological features of 3160 liver tumors underwent surgical resection were analyzed by routine pathology. A total of 25 tumors originating from the three germ layers were involved. Results There were 4 cases of hepatic tumor-like lesions, 112 cases, accounting for 3.5%, 10 benign tumors in the liver, 499 cases accounting for 15.8%, 11 cases of hepatic malignancy and 2549 cases, accounting for 80.7%. The most common of the three groups were inflammatory pseudotumor (73.2% of the group), hepatic cavernous hemangiomas (74.3% of the group), and hepatocellular carcinoma (96.8% of the group). %). The three groups of patients differed in age and sex ratio. The positive rates of serum HBsAg and hepatic cirrhosis in hepatocellular carcinoma were 74.4% and 72.0%, respectively. The combined rate of hepatic cirrhosis in small hepatocellular carcinoma was 83.2%. Conclusions The results show that HBV infection and cirrhosis are closely related to the occurrence of hepatocellular carcinoma.