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接种狂犬病疫苗预防狂犬病已取得明显效果,但注射羊脑组织疫苗引起神经系统并发症者较多。现将我科1975～1980年收治的22例分析报告如下:一、一般情况(一)年龄与性别最小5岁,最大14岁,学龄期儿童21例。其中男15例,女7例。(二)注射针数与发病关系最少只注射4针,最多为18针,以注射6～15针即发病者居多,有16例。发病时间最早为注射后第3天,最迟为第30天。二、临床表现(一)症状开始均有头痛、发热、恶心、呕吐等前驱症状,继之出现神经系统症状,如排尿困难(16例)、嗜睡(10例),少数病例有失语及昏迷。(二)体征出现颈部强直18例,尿潴留或大小便失禁16例,面神经麻痹11例,截瘫8例,偏瘫7例,呼吸肌麻痹4例,视力障碍4例,克氏征,巴氏征,布氏征阳性2例。
Rabies vaccination against rabies vaccination has achieved significant results, but injection of sheep brain tissue vaccine caused more neurological complications. Now my department from 1975 to 1980 admitted 22 cases as follows: First, the general situation (A) of the youngest age and sex 5 years old, up to 14 years old, 21 cases of school-age children. There were 15 males and 7 females. (B) the number of injection needle and the incidence of at least only 4 injection, up to 18 needles to inject 6 to 15 the incidence of those who are mostly, there are 16 cases. The onset of the earliest injection after the first 3 days, at the latest for the first 30 days. Second, the clinical manifestations (a) symptoms are headache, fever, nausea, vomiting and other precursor symptoms, followed by neurological symptoms such as dysuria (16 cases), lethargy (10 cases), a few cases of aphasia and coma. (B) signs of stiff neck 18 cases, urinary retention or incontinence in 16 cases, facial nerve paralysis in 11 cases, 8 cases of paraplegia, hemiplegia in 7 cases, 4 cases of respiratory muscle paralysis, visual impairment in 4 cases, Kirschner sign, pasteurized Sign, Brinell sign positive in 2 cases.