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目的了解平远县2009-2013年手足口病的流行病学和病原学特征,为手足口病的防控提供依据。方法利用《国家疾病监测信息报告管理系统》,对2009-2013年平远县手足口病疫情资料进行描述性流行病学分析,实时荧光RTPCR进行病原学检测。结果 2009-2013年平远县共报告手足口病2 349例,年均发病率为180.16/10万,其中重症病例3例,无死亡病例;男性病例1 451例,女性病例898例,男、女病例数之比为1.62∶1;报告病例以<6岁儿童为主(93.36%),散居儿童和托幼儿童居多,分别占病例数的81.74%和15.50%;发病季节集中在5-7月(60.46%);石正镇年均发病率最高,为267.08/10万,明显高于全县年均发病率;2010-2013年共检测病例55例,其中21例为肠道病毒阳性(38.18%),2010-2012年以EV71(9/21,42.86%)为主,2013以其他EV(11/21,52.38%)为主。结论平远县2009-2013年手足口病发病有明显的季节性、年龄和地区差异,5岁以下散居和托幼儿童是手足口病防控的重点对象,手足口病病原由EV71为主向多种其他肠道病毒共感染转变,需要继续加强手足口病病原学监测工作。
Objective To understand the epidemiological and etiological characteristics of hand, foot and mouth disease from 2009 to 2013 in Pingyuan County, and to provide basis for prevention and control of hand-foot-mouth disease. Methods Using the National Disease Surveillance Information Reporting Management System, a descriptive epidemiological analysis was conducted on the epidemic data of HFMD in Pingyuan County from 2009 to 2013, and the etiological detection was performed by real-time fluorescence RTPCR. Results A total of 2 349 HFMD cases were reported in Pingyuan County from 2009 to 2013, with an average annual incidence of 180.16 / 100 000, of which 3 were severe cases without any deaths; 1 451 were male and 898 were female, The number of female cases was 1.62:1. The reported cases were mainly children aged <6 years (93.36%), the majority of scattered children and nursery children, accounting for 81.74% and 15.50% of cases respectively. The incidence season was concentrated in 5-7 Month (60.46%). The average annual incidence rate of Shi Zhengzheng was the highest (267.08 / 100000), which was significantly higher than the average annual incidence in the county. A total of 55 cases were detected in 2010-2013, of which 21 were positive for enterovirus 38.18%), EV71 (9/21, 42.86%) in 2010-2012, and other EVs (11 / 21,52.38%). Conclusion The incidence of hand, foot and mouth disease in Pingyuan County was significantly different from that in 2009 to 2013. The prevalence of hand, foot and mouth disease was mainly from EV71 A variety of other enterovirus co-infections change, need to continue to strengthen hand foot-mouth disease etiology monitoring.