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加用纳洛酮0.03-0.05mg/(kg·d)于10%葡萄糖100mL静脉滴注,治疗流行性乙型脑炎21例(男性12例,女性9例,年龄4±s5a),治愈率100%。单用常规(利巴韦林和甘草甜素)治疗23例(男性11例,女性12例;年龄3.5±1.4a)作对照,治愈率为87%。2组疗效比较差别无显著意义(P>0.05)。但在退热,止痉,神志转清方面用纳洛酮组明显优于不用纳洛酮的常规疗法组(P<0.01)。
Plus naloxone 0.03-0.05mg / (kg · d) in 10% glucose 100mL intravenous infusion, the treatment of Japanese encephalitis in 21 cases (12 males and 9 females, age 4 ± s5a) , Cure rate 100%. Twenty-three patients (11 males and 12 females; age 3.5 ± 1.4 years) were treated with conventional (ribavirin and glycyrrhizin) controls, with a cure rate of 87%. There was no significant difference between the two groups (P> 0.05). However, naloxone group was significantly better than naloxone-free conventional therapy group (P <0.01) in antipyretic, antispasmodic and mind-clearing.