Minocycline inhibits neuroinflammation and enhances vascular endothelial growth factor expression in

• 作 者: Zhiyou Cai Yong Yan Changyin Y
• 机 构: DepartmentofNeurology,DepartmentofNeurology
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2008年10期
• 关键词: 脑缺血 脑损伤 炎症 二甲胺四环素 血管内皮生长因素 cerebral ischemia/reperfusion inflammation minocyclin
• 基金项目: ACKNOWLEDGEMENTS This study was supported in part by High Technology Research Center, Chongqing Medical University, a fund for basic research from the Ministry of Civil Affairs, China （2007-18-3-05）.

BACKGROUND: Brain ischemia involves secondary inflammation, which significantly contributes to the outcome of ischemic insults. Vascular endothelial growth factor (VEGF) may play an important role in the vascular response to cerebral ischemia, because isc