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目的分析甲型H1N1流感患者免疫学指标的特点。方法以明确诊断的87例甲型H1N1流感患者为研究对象,比较疾病急性期、恢复期部分免疫学指标变化情况,并进行统计学分析。结果在病程急性期,淋巴细胞总数、CD4+T淋巴细胞、CD8+T淋巴细胞及B淋巴细胞计数明显下降。随着病情的恢复,以上指标均明显上升;总补体溶血活性CH50在整个病程中均处于较高水平。结论在甲型H1N1流感病程中,机体细胞免疫起着重要作用。
Objective To analyze the characteristics of immunological indicators in patients with influenza A (H1N1). Methods A total of 87 patients with confirmed type A (H1N1) influenza were enrolled in this study. The changes of some immunological indexes at acute and convalescent phases were compared and statistically analyzed. Results In the acute phase of the disease, the total number of lymphocytes, CD4 + T lymphocytes, CD8 + T lymphocytes and B lymphocytes decreased significantly. With the recovery of the disease, the above indicators were significantly increased; total complement hemololytic activity CH50 throughout the course of a high level. Conclusion In the course of influenza A (H1N1), cellular immunity plays an important role.