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作者在Abbassia Fever Hospital进行的两项研究中,发现用ceftriaxone治疗由奈瑟氏脑膜炎球菌、肺炎链球菌和嗜血杆菌所致的脑膜炎是非常有效、安全且能为病人所接受的。第一项研究是成人患者,从静脉给ceftriaxone;第二项研究是儿童患者从肌肉给药。剂量100mg/kg/天(最大量4g)连用6天。与氨苄加氯霉素联用组进行比较,结果与Peltola等报告相似。两个组在治疗开始后虽然脑脊液革兰氏染色涂片中可见到细菌,但细
In two studies conducted by the authors at Abbassia Fever Hospital, it was found that ceftriaxone was very effective, safe and patient-acceptable for the treatment of meningitis caused by Neisseria meningitides, Streptococcus pneumoniae and Haemophilus. The first study was an adult patient who was given ceftriaxone intravenously; the second was a pediatric patient who was given muscle. Dose 100mg / kg / day (maximum 4g) for 6 days. Compared with ampicillin plus chloramphenicol, the results were similar to those reported by Peltola et al. Although the bacteria were found in Gram-positive smears of cerebrospinal fluid after the treatment started in both groups, the two groups were fine