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目的探讨穿刺活检病理诊断前列腺癌的形态学观察特征。方法 2010年10月至2011年10月期间,我院诊治的130例前列腺疾病患者,均给予前列腺穿刺活检检查,其中70例进行了免疫组化检查,对其病例进行回顾性分析。结果 130例穿刺患者中,除了51例确诊为前列腺癌(39.2%)外,其余78例为前列腺良性增生(60.0%),1例为其他炎性病变(0.8%);确诊为前列腺癌的51例患者中,出现结构紊乱的有49例(96.1%)、细胞学异型性的有35例(68.6%)、浸润的有46例(90.2%);51例前列腺癌患者中,高分化腺癌有10例(19.6%),中分化腺癌有l5例(29.4%),低分化腺癌有26例(51.0%)。结论对于前列腺癌患者,前列腺穿刺活检根据病理形态学特征,做出诊断的一种相对有效的诊断方法。
Objective To investigate the morphological characteristics of prostate cancer by needle biopsy. Methods From October 2010 to October 2011, 130 cases of prostatic diseases diagnosed and treated in our hospital were examined by prostatic biopsy. Among them, 70 cases were examined by immunohistochemistry and their cases were retrospectively analyzed. Results Of the 130 patients with prostatic cancer, 51 were diagnosed as prostate cancer (39.2%), and the other 78 were benign prostatic hyperplasia (60.0%) and 1 were other inflammatory lesions (0.8%). Of the patients, 49 (96.1%) had structural disorders, 35 (68.6%) had cytologic atypia, and 46 (90.2%) had infiltration. Among 51 prostate cancer patients, well-differentiated adenocarcinoma There were 10 cases (19.6%), moderately differentiated adenocarcinomas (29.4%), and poorly differentiated adenocarcinomas 26 (51.0%). Conclusions Prostate biopsy is a relatively effective diagnostic method for diagnosis of prostate cancer patients based on the pathomorphological features.