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采用改良的Ellman法测定46例脑性瘫痪（CP）儿童及34例正常对照儿童红细胞膜乙酸胆碱酯酶（EM-AChE）和血浆丁酰胆碱酯酶（PI-BchE）活性，结果CP儿童EM-AchE和P1-DehE活性明显下降，并与病情程度有关，中、重度组CPEM-AchE活性明显低于轻度组和对照组，重度组P1-BchE活性明显低于轻度组和对照组，重度组P1-BchE活性明显低于其它3组.认为这种异常对CP-系列临床表现如运动障碍、智力低下和脑电活动异常可能有一定的影响.
Ellman method was used to determine the activity of erythrocyte membrane acetylcholinesterase (EM-AChE) and plasma butyrylcholinesterase (PI-BchE) in 46 children with cerebral palsy (CP) and 34 children with normal control. Results CP The activities of EM-AchE and P1-DehE in children were significantly lower than those in mild group and control group The activity of P1-BchE in group and severe group was significantly lower than those in the other three groups, which may be thought to have a certain impact on CP-series clinical manifestations such as dyskinesia, mental retardation and abnormal EEG activity.